PeaKDEck: a kernel density estimator-based peak calling program for DNaseI-seq data
نویسندگان
چکیده
منابع مشابه
PeaKDEck: a kernel density estimator-based peak calling program for DNaseI-seq data
Hypersensitivity to DNaseI digestion is a hallmark of open chromatin, and DNaseI-seq allows the genome-wide identification of regions of open chromatin. Interpreting these data is challenging, largely because of inherent variation in signal-to-noise ratio between datasets. We have developed PeaKDEck, a peak calling program that distinguishes signal from noise by randomly sampling read densities...
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ژورنال
عنوان ژورنال: Bioinformatics
سال: 2014
ISSN: 1460-2059,1367-4803
DOI: 10.1093/bioinformatics/btt774